CASE STUDY

Antibody-Drug Conjugates

Meet your method development and sample testing needs for payloads and biologics for all phases of drug development.

Access our 20+ years of ADC experience, including preclinical through FDA approval of LC/MS and LBA assays for payloads and biologics.

When a complex ADA assay failed at two prior CROs, the sponsor turned to BioAgilytix for help. See how we applied a novel approach to overcome target interference challenges on a tight deadline.

What You'll Learn:
  • How BioAgilytix conducted the GCP study evaluating the drug for multiple indications.
  • An in-depth overview of the innovative solution BioAgilytix created to overcome target interference challenges caused by dimerization.
  • How the assay got back on track, and how this same solution can be applied to other studies, such as oncological programs.
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Services

Ready-to-go Methods Save Time and Money

  • Support for rapid LC/MS method development and sample testing leveraging our broad small molecule experience
  • Begin sample testing quickly for your PK and ADA assays leveraging our immunogenicity (cell-based NAb) assay experience 
Trust a Team of Scientific Experts to Deliver Cohesive, High-quality Bioanalytical Results
  • Benefit from working with a single team that drives both the assay development and sample testing
  • Work with Project Managers who directly coordinate all your critical assay work, ensuring on-time deliverables according to your priorities and requirements
Optimal Platforms for ADC Development
  • Sciex Triple Quad™ 7500 LC-MS/MS with Exion 2.0+ UHPLC
  • Sciex ZenoTOF 7600 with Sciex ECHO®MS+ or Waters ACQUITY Premier UPLC®
  • Thermo Scientific Orbitrap Exploris 240 with Vanquish Flex UHPLC
  • Waters Xevo TQ-S LC-MS/MS System with Acquity UPLC

 

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Our ADC Services Include

Pharmacokinetics 

Rely on a team of experienced scientists to develop PK assays and generate reproducible and reliable results to support your drug program. 

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Immunogenicity

Optimize drug safety with industry-leading immunogenicity and testing expertise to advance your program.

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Biomarkers

Improve clinical trial efficacy and safety with comprehensive, fit-for-purpose biomarker analysis for your program.

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Ready to Start Your Project?

Our scientists are available to discuss your ADC project and how our bioanalytical CRO can help you streamline the drug development process.

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